Simon Trowitzsch

Dr. Simon Trowitzsch is a Group Leader at the Institute of Biochemistry at Goethe-University Frankfurt, where he also serves as a Senior Scientist collaborating with Prof. Robert Tampé. His research focuses on ribonucleoprotein complexes, antigen processing mechanisms, and enabling technologies for studying multiprotein complexes. He holds a PhD in Biochemistry from Georg-August University Göttingen and Max-Planck Institute for Biophysical Chemistry, and a Diploma in Biochemistry from Georg-August University.

Dr. Trowitzsch leads a team (TrowitzschLab) investigating fundamental aspects of gene expression and immune system function. His work integrates structural biology, molecular biology, and advanced biophysical techniques. Notable achievements include structural studies of the MHC-I peptide-loading complex and discoveries in tRNA splicing ligase mechanisms.

• Research Interests:
  • Ribonucleoprotein complexes in gene expression
  • Antigen processing pathways in adaptive immunity
  • Development of tools for multiprotein complex analysis
• Key Awards:
  • Marie-Curie Intra-European Fellowship (2010–2012)
  • Max-Planck Research Stipend (2008–2009)
• Funding:
  • DFG Grant on tRNA Biogenesis
  • Associated Member of Collaborative Research Center 902

His group actively collaborates with institutions like the European Molecular Biology Laboratory (EMBL) and employs cutting-edge methods such as cryo-EM and mass spectrometry. Future work aims to bridge structural insights with functional studies of immune-related complexes.