معرفی
Simon Halegoua is a Professor at Stony Brook University's Renaissance School of Medicine, Department of Neurobiology & Behavior. He earned his PhD in Molecular Biology from SUNY Stony Brook in 1978 and has held academic positions there since 1982, including Interim Chair (2006-2008) and Director of the Center for Nervous System Disorders since 2002.
- Education:
- B.S. in Biochemistry, Stony Brook University (1974)
- Ph.D. in Molecular Biology, Stony Brook University (1978)
- Postdoctoral Fellow, Salk Institute (1978-1982)
His research focuses on neurotrophin signaling, particularly how Nerve Growth Factor (NGF) and Trk receptors regulate neuronal survival, axon growth, and synaptic strength through retrograde signaling endosomes. He pioneered the model of endosomal signaling and discovered the Pincher protein, critical for endosome formation and long-distance axonal transport.
The 15 most recent publications highlight his work on retrograde signaling (via endosomes and Pincher), sodium channel regulation in peripheral neurons, and signal transduction dynamics involving Ras, Raf, and Trk receptors. Key subfields include endocytosis, neuronal growth cones, and phospholipid metabolism in signaling compartments.
Professor Halegoua has served on editorial boards for Journal of Neuroscience and Journal of Biological Chemistry. His lab personnel include research technicians like Wendy Akmentin, though no formal advisees are listed in the provided texts.
