معرفی
Bettina Kalisch is an Associate Professor in the Department of Biomedical Sciences at the Ontario Veterinary College (OVC), University of Guelph. She holds a BSc, MSc, and PhD from Queen's University. Her research focuses on mechanisms regulating genes critical to cholinergic neuron function and Alzheimer Disease, including nerve growth factor signaling, nitric oxide effects, and oxidative stress impacts on gene expression. Key targets include cholinergic genes, amyloid precursor protein, tau, LDL receptor-related protein, and apolipoprotein E.
Education:
- PhD, Queen's University
- MSc, Queen's University
- BSc, Queen's University
Her lab investigates neurotrophin signaling pathways and epigenetic modifications affecting neuronal gene expression. Recent work explores cross-talk between NGF signaling, nitric oxide pathways, and transcriptional regulation in neurodegenerative contexts. Collaborations address how environmental stressors like oxidative stress influence disease-related gene expression patterns.
Current graduate students include Helen Chen (MBS), Shreya Prakash (MSc), and Daniel Stenn (MSc). Her laboratory is located in BIOM 1671A OVC with an office in BIOM 1646F. Research outputs span neurochemistry, molecular biology, and cellular neuroscience, with emphasis on translational insights into Alzheimer's mechanisms.
