Shernan G Holtan

Shernan G Holtan is an Adjunct Associate Professor in the Department of Medicine - Hematology, Oncology, Transplant at the University of Minnesota. His research focuses on Graft-versus-host Disease (GVHD), aging, sarcopenia, and Bone Marrow Transplantation (BMT).

• Research Trends: His work addresses GVHD biomarker development (e.g., Amphiregulin, ST2, REG3α), prophylaxis strategies (PTCy + Sirolimus), and post-transplant health outcomes in pediatric and adult populations.
• Projects: He leads studies on GVHD treatment (Ruxolitinib, Axatilimab), CD83-targeted therapies to reduce leukemia relapse, and health informatics-based self-management programs for transplant survivors.
• Collaborations: Partnered with Vitrac Therapeutics LLC, Incyte Corporation, Syndax Pharmaceuticals, and NIH.