Shawn Gomez

Dr. Shawn Gomez is a Professor in the Lampe Joint Department of Biomedical Engineering at UNC-Chapel Hill and North Carolina State University and in the Department of Pharmacology at UNC-Chapel Hill. He serves as the Executive Director of FastTraCS, a component of the NC TraCS Institute funded through the NIH CTSA Program, and is a UNC Lineberger Comprehensive Cancer Center member.

His educational background includes a PhD in Biomedical Engineering from Columbia University (1999), an MS in Aerospace Engineering Sciences from the University of Colorado, Boulder (1993), and a BS in Aerospace Engineering Sciences from the same institution (1990). He completed postdoctoral training in Bioinformatics and Computational Biology at the Judith P. Sulzberger Columbia Genome Center and Institut Pasteur in Paris.

Dr. Gomez's research spans systems biology, network pharmacology, and translational AI, with a focus on understanding cell signaling architecture in human disease. His lab develops computational approaches for network pharmacology and targeted cancer therapies, along with machine learning methodologies to address clinical needs and enhance clinical decision making. The research integrates computational modeling with experimental approaches to improve diagnostic and therapeutic interventions.

His recent publications reveal a strong focus on kinome research, particularly in pancreatic cancer and understudied kinases, with increasing integration of machine learning techniques for predicting clinical outcomes and kinase-substrate relationships. The work spans from fundamental systems biology to translational applications in cancer therapeutics and surgical outcomes prediction.

Scientific Awards:

• Leadership Advanced Program, UNC-Chapel Hill 2017
• Chancellor's Entrepreneurship Boot Camp 2015
• ACCLAIM Scholar (Academic Career Leadership Academy in Medicine) 2013-2014
• UNC Research Council Award 2011
• Carl Storm URM Fellowship 2008
• UNC Junior Faculty Development Award 2006
• Florence Gould Scholar 2005
• Pasteur Foundation Fellow 2002-2005

Dr. Gomez directs the Gomez Lab, which focuses on systems biology, network pharmacology, and translational AI. The lab maintains several key resources including Darkkinome.org, FAAS, and IAS servers for kinome research. His work bridges computational biology with clinical applications, particularly in cancer therapeutics and surgical outcomes prediction through machine learning approaches.