معرفی
Shaodong Guo is a Professor in the Department of Nutrition at Texas A&M University's College of Agriculture & Life Sciences, and a Presidential Impact Fellow. His research focuses on insulin signaling pathways, metabolic homeostasis, and cardiovascular dysfunction. He leads the Guo Laboratory, investigating mechanisms linking insulin resistance to diabetes, obesity, and organ failure through PI3K→Akt→FoxO pathways.
Education:
- B.S. in Agronomy, Huazhong Agricultural University (1989)
- Ph.D. in Physiology, Peking University (1995)
Research Interests:
- Molecular mechanisms of insulin resistance and cardiovascular dysfunction
- FoxO transcription factor roles in metabolic regulation
- Nutritional/therapeutic interventions for metabolic disorders
- Genetic engineering models to study tissue-specific insulin action
Awards:
- 2015 American Diabetes Association Career Development Award
- Multiple Young Investigator Awards (1999)
- Guanghua Scholarship (1995)
Lab & Collaborations: His lab uses genomic, proteomic, and metabolomic approaches in mice models to explore insulin/glucagon signaling, with a focus on FoxO1's role in liver, heart, and pancreatic β-cells. Current projects include developing bioactive compounds to enhance insulin sensitivity and studying TGF-β1's impact on metabolic pathways.
