Claudia Carmone

Claudia Carmone is a Lecturer in the Department of Human and Animal Physiology, actively researching molecular mechanisms in protein and lipid metabolism with implications for cardiovascular and muscular physiology.

Her research interests span Molecular Biology, Biochemistry, and Physiology, focusing on:

• FOXO1 and AKT-mTORC1 signaling pathways
• Nicotinamide nucleotide transhydrogenase (NNT) dysfunction
• Hypoxia-induced protein degradation
• Lipid metabolism in skeletal muscle
• Neuromuscular junction integrity in developmental models

She primarily utilizes 24-day-old murine models to investigate metabolic stressors.

Recent publications (2024-2025) reveal a concentrated effort on NNT's role in mitochondrial metabolism and hypoxia responses, demonstrating how metabolic disruptions alter protein catabolism and neuromuscular development. Key findings include FOXO1 activation under hypoxia and NNT's critical function in lipid homeostasis.