Shalini Sharma

Shalini Sharma, PhD, serves as a Research Fellow in the Department of Diagnostic Radiology and Nuclear Medicine, specializing in molecular imaging probe development and radiopharmaceutical applications. Her work bridges nuclear medicine, nanotechnology, and therapeutic monitoring with emphasis on translational research.

Her primary research domains include Molecular Imaging, Radiopharmaceuticals, Nanomedicine, Theranostics, Nuclear Medicine, Neuroimaging, and Infection Imaging. She pioneers novel PET tracers for tracking viral vectors, differentiating bacterial infections from sterile inflammation, and monitoring cell-based therapies. Her methodology integrates radiochemistry, nanomaterial engineering, and in vivo validation to address challenges in blood-brain barrier penetration, neuroinflammation imaging, and infection diagnostics.

Analysis of her 2019-2025 publications reveals consistent innovation in zirconium-89 radiometal applications for tracking AAV vectors, white blood cells, and stem cells. Key thematic threads include: (1) blood-brain barrier modulation strategies for neurotherapeutics, (2) dual-modality nanoparticle systems for combined imaging and antibacterial action, and (3) platform technologies for real-time monitoring of alpha radionuclide therapy. Her work demonstrates exceptional technical breadth across radiochemistry, nanomaterial design, and preclinical validation.