Severine Le Gac

Severine Le Gac is a Full Professor at the University of Twente, affiliated with the TechMed Centre and leading the Applied Microfluidics for BioEngineering Research group. Her work bridges engineering and biomedical sciences through innovative microfluidic platforms.

Her research interests focus on the development and application of microfluidic systems for bioengineering, particularly organ-on-chip technologies. These platforms enable precise control over cellular microenvironments for applications in disease modeling, drug testing, and fundamental biological studies. Key areas include fibrosis-on-chip, lung-on-chip, and advanced cell imaging substrates.

The recent publications reflect a strong trend toward developing physiologically relevant in vitro models using microfabrication and hydrogel technologies. Her work integrates engineering design with biological functionality, emphasizing applications in toxicology, regenerative medicine, and high-resolution imaging. The research spans from fundamental device development to translational applications in human health.

She actively contributes to the scientific community through invited talks and editorial roles, demonstrating leadership in the lab-on-a-chip field. Although specific grant details are not listed, her sustained research output and invited presentations suggest successful funding and collaborative engagement.

Le Gac leads a research team focused on advancing microfluidic bioengineering solutions, contributing significantly to the TechMed Centre's mission of translating medical technology to clinical practice. Her group develops novel devices that mimic human organ functions for improved experimentation and therapeutic development.