معرفی
Seham Ebrahim is an Assistant Professor in the Department of Molecular Physiology and Biological Physics at the University of Virginia School of Medicine. Her research focuses on the cytoskeletal architecture and dynamics that underpin cellular physiology and disease, particularly through high-resolution live cell and tissue imaging.
Education:
- BS in Biotechnology, University College London
- MS in Biotechnology, Hamburg University of Technology
- PhD in Biological Sciences, Queen Mary University of London
Research Interests: Dr. Ebrahim investigates cellular mechanobiology in two systems: the intestinal epithelium (dynamic barrier function under mechanical stress) and spermatogenesis (mechanosensitive membrane remodeling). Her work bridges cell biology, biophysics, and mucosal immunology.
Grant Support: A $2 million NIH R35 MIRA grant funds her mechanosensing research in the gut, with implications for Inflammatory Bowel Disease (IBD), colorectal cancer, and male infertility. Her lab employs super-resolution live imaging, cryo-ET, and mouse genetics.
Scientific Contributions: Notable discoveries include the hemifusome (a novel organelle in cellular trafficking) and the role of septin 9 in intestinal diseases. Her team includes graduate students Sharon Zheng and Dominik Robak, and former trainees Khosiyat Makhmudova and Yuta Ohno.
