Seema Singhal

Dr. Seema Singhal serves as Professor of Medicine in Hematology and Oncology at Northwestern University's Feinberg School of Medicine, holding the distinguished Chez Family Professorship of Myeloma Research. She practices at Northwestern Memorial Hospital's Arkes Family Pavilion and leads critical clinical research in plasma cell malignancies.

Her research focuses on multiple myeloma, CAR T-cell therapies, and hematopoietic stem cell transplantation. Current investigations include cardiotoxicity monitoring in immunotherapy, cytogenetic testing standardization, and genomic studies of myeloma in diverse populations. Her work bridges clinical practice with translational research to improve outcomes for plasma cell disorder patients.

Dr. Singhal's recent publications reveal strong emphasis on

• Real-world implementation of novel myeloma therapies
• Addressing diagnostic disparities in cancer care
• Genetic risk factors across ethnic populations
• Development of evidence-based treatment guidelines

Her scientific recognition includes:

• Chez Family Professorship of Myeloma Research
• Contributing authorship to NCCN Guidelines for Multiple Myeloma

She actively leads multiple clinical trials including expanded access programs for nonconforming CAR-T products (idecabtagene vicleucel, ciltacabtagene autoleucel) and circulating plasma cell monitoring studies. Her work involves significant collaboration with the Robert H. Lurie Comprehensive Cancer Center and pharmaceutical industry partners.

Dr. Singhal directs research programs focused on

• Serial monitoring of circulating plasma cells
• Access to investigational CAR-T therapies
• Genomic profiling of myeloma variants