معرفی
Sebastian Schneeweiss is Professor of Medicine and Epidemiology at Harvard Medical School and Harvard T.H. Chan School of Public Health, and Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital. His work focuses on the comparative effectiveness and safety of biopharmaceuticals using complex healthcare databases, with particular emphasis on methodological innovations for real-world evidence generation.
Dr. Schneeweiss received his medical training at the University of Munich Medical School and his doctoral degree from Harvard. He teaches advanced courses including Database Analytics for Pharmacoepidemiology (EPI286) and Effectiveness Research in Longitudinal Healthcare Databases (EPI253) at Harvard, training the next generation of researchers in cutting-edge methods for healthcare data analysis.
His research program is funded by multiple NIH, PCORI, BWF, and FDA grants, focusing on developing and applying analytic methods to improve the scientific validity of epidemiologic analyses using complex longitudinal healthcare databases. His work spans multiple therapeutic areas including cardiovascular medicine, oncology, dermatology, and respiratory diseases, with a consistent emphasis on rapid-cycle analytics for medication safety monitoring and comparative effectiveness research.
Dr. Schneeweiss's recent publications (2024-2025) demonstrate strong trends toward methodological innovation in trial emulation, calibration of real-world evidence against randomized trials, and the application of advanced analytics including natural language processing to healthcare databases. His work is increasingly focused on creating standardized frameworks for using real-world evidence to support regulatory decision-making globally.
- Fellow of the American College of Epidemiology
- Fellow of the American College of Clinical Pharmacology
- Fellow of the International Society for Pharmacoepidemiology
- Past President of the International Society for Pharmacoepidemiology
As Principal Investigator on multiple large-scale grants, Dr. Schneeweiss leads the FDA-funded Sentinel Innovation Center and serves as a voting consultant to the FDA Drug Safety and Risk Management Advisory Committee. As co-founder and Science Advisor of Aetion Inc., he develops rapid-cycle analytics platforms for healthcare database networks worldwide. His research group mentors numerous students and postdoctoral fellows working at the intersection of epidemiology, biostatistics, and healthcare data science.
The Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital, which he leads, serves as a world-leading research and training center that collaborates with the FDA, pharmaceutical companies, and international research networks to advance methods for using real-world data in regulatory and clinical decision-making.
