Sebastian Brandner

Sebastian Brandner is Professor of Neuropathology at the University College London (UCL) Institute of Neurology and Honorary Consultant Neuropathologist at University College London Hospitals NHS Foundation Trust. His career spans groundbreaking research in prion diseases, neurodegenerative disorders, and brain tumor pathogenesis, with over 610 publications and leadership roles in national and international medical organizations.

• Doctor of Medicine, Georg-August-Universität Göttingen (1991)
• Habilitation, University of Zurich (2000)
• Fellow of the Royal College of Pathologists (2002)

His research focuses on:

• Prion disease mechanisms and BSE/vCJD transmission
• Amyloid Beta pathogenesis in Alzheimer's and iatrogenic transmission
• Brain tumor origin, molecular profiling, and genotype-phenotype correlations
• Development of mouse models for glioma research

Recent publications highlight his work on DNA methylation classification (Nature 2018), amyloid-beta transmission through medical procedures (Nature 2015, Acta Neuropathologica 2018), and glioma genetics (Acta Neuropathologica 2019, Cancer Research 2019). His work bridges molecular pathology, translational research, and clinical diagnostics.

Scientific Recognition:

• Fellow of the Academy of Medical Sciences (2022)
• Key contributor to WHO CNS tumor classification and Royal College of Pathologists guidelines

Academic Leadership:

• Training Programme Director in Diagnostic Neuropathology, London
• Chair of Specialty Advisory Committee and Working Group of Cancer Services, Royal College of Pathologists
• Former French National Cancer Institute Scientific Advisory Board Chair