Scott Widenmaier

Dr. Scott Widenmaier serves as Associate Professor in the Department of Anatomy, Physiology and Pharmacology at the University of Saskatchewan, conducting research at the molecular interface of cellular stress and metabolic homeostasis.

His immunometabolism research program investigates how obesity-induced nutrient stress triggers chronic inflammation leading to diseases like diabetes and fatty liver disease. Key focus areas include:

• Stress-adaptive transcription factors in metabolic regulation
• Cellular cholesterol homeostasis mechanisms
• Obesity-related inflammatory pathways
• Multidisciplinary approaches spanning molecular biology to physiology

Using in vitro and in vivo models, the lab systematically identifies intervention points where mitigating metabolic stress could prevent disease progression. Current work centers on two major projects examining transcription factor roles in fatty liver disease and fundamental cholesterol regulation mechanisms.

Prospective graduate students must submit detailed statements of interest with transcripts and references. While specific grant details aren't provided, the active research program indicates ongoing funding supporting trainee positions in this critical area of metabolic health research.