Sara Mandatori

Sara Mandatori is a Researcher at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen, working within the Issazadeh-Navikas Group. Her laboratory is located at Ole Maaløes Vej 5, 2200 København N., with contact available via email sara.mandatori@bric.ku.dk and phone numbers +4535335324/+4591772189.

Her research spans cancer biology and immunology, with core expertise in:

• Regulatory T cell differentiation mechanisms
• Hepatocellular carcinoma pathogenesis
• Metabolic rewiring in tumor immunity
• Autophagy/mitophagy in cancer therapy
• Lipid metabolism and oxidative stress responses

She investigates how metabolic pathways like PRKAG2.2 signaling and oleic acid metabolism influence immune regulation and tumor progression.

Analysis of her 2020-2023 publications reveals a progressive focus on liver cancer immunometabolism, with her 2023 Science Advances paper establishing PRKAG2.2 as a key regulator in FoxA1+ T cells. The 2021 Frontiers paper (78 Scopus citations) demonstrated oleic acid's anti-tumor effects through autophagy reduction, gaining significant media attention including news coverage and X discussions.

Scientific awards:

• No awards or fellowships documented in available sources

Advising and grants:

• No student mentoring or grant information provided

Laboratory context:

• Active member of Issazadeh-Navikas Group at BRIC
• Collaborates internationally on hepatocellular carcinoma research
• Focuses on translational cancer immunology mechanisms