SangKon Oh

SangKon Oh, Ph.D., is a Professor of Immunology at Mayo Clinic in Phoenix, Arizona, within the Department of Research. His laboratory investigates the role of the innate immune system—particularly dendritic cell and regulatory B cell subsets—in shaping adaptive immune responses in health and disease.

His research focuses on understanding the molecular and cellular phenotypes of human dendritic cells in tissue microenvironments such as skin, lungs, and genital tract, and how these cells regulate type 1 interferon expression and antigen-specific immunity or tolerance. These studies are applied to vaccine and therapeutic development for cancers, microbial infections, autoimmune diseases, and transplantation rejection.

Dr. Oh’s work also explores mechanisms of donor-specific antibody-mediated rejection in solid organ transplantation and the immunobiology of regulatory B cells. His integrative approach bridges basic immunology with translational applications, contributing significantly to regenerative biotherapeutics and patient care innovation.

The trends in his research, though specific articles are not listed, center on human immunology, immune regulation, and therapeutic targeting in chronic inflammatory and immune-mediated diseases. His work is closely aligned with the Center for Regenerative Biotherapeutics and Immunology Research at Mayo Clinic.

• Senior Associate Consultant II-Research, Immunology, Department of Research

Dr. Oh advises researchers in immunology and contributes to postdoctoral training at Mayo Clinic. While specific grants are not mentioned, his research is likely supported by institutional and federal funding given the scope and infrastructure described. His laboratory serves as a hub for advanced immunological investigation with clinical translation goals.

He is affiliated with key research entities including the Center for Regenerative Biotherapeutics and participates in Mayo Clinic’s broader research infrastructure such as core facilities, clinical trials, and training grant programs.