Sandrine Lévêque-Fort

Sandrine Lévêque-Fort is a Researcher at the Institut des sciences moléculaires d'Orsay (ISMO) under Université Paris-Saclay and CNRS. She also serves as the Chief Science Officer (CSO) at the startup Abbelight, which develops fluorescence optical microscopy instruments for biological research. Her work bridges academic research in optics with industrial applications, focusing on super-resolution microscopy techniques.

• Research Focus: Development of advanced optical imaging methods for cellular and neuronal observation, including SAF (Supercritical Angle Fluorescence) and ModLoc (Modulation Localization).
• Key Collaborations: LabEx PALM, SATT Paris Saclay, Institut Langevin.
• Scientific Awards:
  • Irène Joliot-Curie Prize (2020) in the 'Women, research and enterprise' category with a €15,000 endowment.
• Students: Supervised PhD student Nicolas Bourg, co-founder of Abbelight.
• Instrumental Developments: Patents for SAF imaging and ModLoc technique enabling 3D reconstruction of biological samples up to 50 microns with uniform resolution.

The articles she has contributed to, such as the ModLoc technique in Nature Photonics (2016), highlight advancements in super-resolution fluorescence microscopy for studying cellular mechanisms in neurodegenerative diseases and oncology. These works span subfields like single-molecule localization, 3D imaging, and neurodegenerative disease modeling.