Ignacio IZEDDIN

Ignacio IZEDDIN is an Associate Professor (Maître de conférences) at the Institut Langevin, ESPCI Paris, which is part of CNRS and Université PSL. His research sits at the critical intersection of advanced optical imaging, biophysics, and molecular cell biology, with a particular focus on pushing the boundaries of what can be visualized and understood about molecular distribution and cellular dynamics.

His primary research interests include Single-Molecule Localization Microscopy (SMLM), super-resolution imaging techniques, single particle tracking (SPT), biophotonics, diffusion processes in cell biology, molecular cell biology, transcription regulation, DNA repair mechanisms, and light-matter interactions at the nanoscale. Dr. IZEDDIN's work aims to develop innovative microscopy tools that overcome current limitations in spatial and temporal resolution, enabling the capture of rapid, dynamic cellular processes with unprecedented clarity.

The trends in his recent publications reveal a strong focus on developing event-based sensor technology for high-speed single-molecule localization, creating novel 3D microstructured substrates for cellular imaging and calibration, studying light-matter interactions at the nanoscale through fluorescence lifetime imaging, and applying these advanced techniques to understand fundamental biological processes like DNA repair, chromatin dynamics, and cellular differentiation. His work consistently bridges physics, engineering, and biology to solve complex imaging challenges.

Dr. IZEDDIN is actively involved in research funding and recruitment, with current projects including a European LIGHTinParis COFUND PhD position analyzing alpha-synuclein diffusion in neurons using super-resolution microscopy based on event sensors, and hiring for a software engineer position to develop data processing tools for event-based SMLM technology.

His laboratory employs a highly interdisciplinary approach, combining physics, biology, and engineering expertise to tackle challenging problems in cellular imaging. Current projects involve collaborations with neuroscientists, physicists, and engineers to study everything from molecular diffusion in neurons to macrophage differentiation on 3D topographical substrates.