Sandra Kan Loo

Dr. Sandra Kan Loo is a Professor-in-Residence in the Department of Psychiatry and Biobehavioral Sciences at UCLA's David Geffen School of Medicine. Her research focuses on neurodevelopmental disorders, particularly ADHD, using neuroimaging and electrophysiological methods to identify biomarkers for diagnosis and treatment.

Research Focus

Dr. Loo's work explores the neural underpinnings of cognitive deficits in ADHD, with emphasis on:

• EEG biomarkers and alpha oscillations in attention regulation
• Neuroimaging correlates of working memory and cognitive control
• Treatment response prediction for pharmacological and neuromodulation therapies
• Comorbidity patterns with tic disorders and OCD
• Developmental trajectories of brain connectivity abnormalities

Research Trends

Her recent publications (2021-2024) demonstrate:

• Advancement in EEG-based diagnostic tools for ADHD subtyping
• Integration of multimodal neuroimaging to study treatment mechanisms
• Development of predictive models for personalized interventions
• Examination of sleep and circadian factors in ADHD pathophysiology
• Cross-disorder comparisons of neural network abnormalities

Research Funding

Dr. Loo has led multiple NIH-funded projects including:

• NIH R01MH116268 (2018-2023): Alpha oscillations and working memory deficits
• NIH R01NS097484 (2016-2021): Brain-behavior relationships in tic disorders
• NIH R21MH119448 (2019-2021): Real-time attention tracking in classrooms
• NIH R34MH101282 (2014-2019): Trigeminal nerve stimulation for ADHD
• NIH R01NS054124 (2006-2012): Genetics of EEG patterns in ADHD