معرفی
Samir El Andaloussi is a Professor of Biomolecular Medicine and Advanced Therapy at Karolinska Institutet, part of the Department of Laboratory Medicine. His research focuses on leveraging biological nanovesicles (exosomes) for drug delivery, particularly RNA therapeutics and gene therapy. He leads the 'Biomolecular Medicine and Advanced Therapies' research group, specializing in exosome engineering to address delivery challenges in modern therapeutics.
- Education: PhD in Molecular Cell Biology (Stockholm University, 2008), Docent at Karolinska Institutet (2018), postdoctoral fellowships at Karolinska Institutet, Stockholm University, and University of Oxford.
- Grants: Includes ERC Consolidator Grant (DELIVER project), Swedish Research Council, SSF-IRC FormulaEx, and collaborations with industry partners like Evox Therapeutics and Novo Nordisk Foundation.
Research interests include exosome-based drug delivery, nanotechnology in medicine, and targeting therapies for neurodegenerative disorders and inflammatory diseases. Notable projects involve in situ engineering of cells to produce therapeutic exosomes and developing mRNA delivery platforms.
Scientific contributions span over 200 publications in journals like Nature Biomedical Engineering and Advanced Materials. His team includes PhD students (e.g., Quentin Vicentini, Houze Zhou) and postdoctoral researchers working on exosome engineering, CRISPR delivery, and biomaterials.
Current initiatives include the DELIVER ERC project, aiming to use engineered exosomes for brain-targeted therapies, and developing exosome-based platforms for mRNA vaccines and targeted cancer treatments.
