معرفی
Sam Siddighi, MD, MS, is a dual-appointed Associate Professor at Loma Linda University School of Medicine, serving in the Departments of Gynecology & Obstetrics and Basic Sciences. He earned his medical degree from New York Medical College in 2001 and a Master of Science from the University of Cincinnati in 2008. His career merges advanced clinical practice in urogynecology with translational research focused on pelvic-floor disorders.
Education
- Doctor of Medicine (MD), New York Medical College — 2001
- Master of Science (MS), University of Cincinnati — 2008
Research Focus
Dr. Siddighi’s scholarly work spans oxidative-stress biology in cervical tissues, neuromodulation therapies for overactive bladder, robotic and minimally invasive pelvic reconstruction, and surgical education. He investigates how biochemical markers, advanced imaging, and novel surgical techniques can improve patient outcomes after prolapse repair and incontinence procedures.
Across 27 peer-reviewed publications from 2004 to 2020, his research exhibits a clear trajectory: early investigations into sperm apoptosis and reproductive outcomes evolved into large clinical cohort studies comparing vaginal versus robotic surgical routes, intravesical electrical stimulation protocols, and peri-operative biomarkers such as serum creatinine for early detection of ureteral injury.
Grants & Industry Collaboration
- Principal Investigator, Boston Scientific Corp. — Randomized trial of robotic sacrocolpopexy vs. high uterosacral ligament suspension (2024-2025)
- Principal Investigator, Boston Scientific Corp. — Multi-center study comparing Solyx™ vs. Obtryx™ sling systems (2017-2018)
- Principal Investigator, LLU Dept. of Gynecology & Obstetrics — Effects of age on post-operative pain after pelvic reconstruction (2011-2012)
- Co-Investigator, LLU Dept. of Anesthesiology — Impact of dextrose on post-operative nausea and vomiting (2013-2014)
Laboratory & Clinical Teams
Dr. Siddighi collaborates closely with multidisciplinary teams including urogynecology fellows, basic-science researchers, robotic surgery engineers, and anesthesiologists at Loma Linda University Medical Center. His work integrates clinical operating-room data with bench-top analyses of cervical and vaginal tissues to drive evidence-based improvements in pelvic-floor care.
