معرفی
Sachin P. Patil is a Professor of Chemical Engineering at Widener University, leading the NanoBio Lab within the School of Engineering. His research focuses on Alzheimer’s disease and cancer therapy, emphasizing drug discovery and protein engineering. He holds a PhD in Chemical Engineering from Michigan State University (2007) and has developed courses in biochemical engineering, thermodynamics, and bioseparations. Patil’s work is supported by grants from the Alzheimer’s Association, W.W. Smith Charitable Trust, and National Cancer Institute.
Research Interests:
His long-term goals include discovering drugs to enhance ApoE lipidation for Alzheimer’s and designing small-molecule inhibitors targeting cancer-related protein interactions (e.g., p53-MDM2, PD-1/PD-L1). Recent breakthroughs include identifying Isobavachin as an ApoE4 structure corrector and developing machine-learning models for cancer immunotherapy drug design.
Awards & Grants:
- New Investigator Research Grant (Alzheimer’s Association, 2013–2015)
- Faculty Development Grant (Widener University, 2014–2015)
Advising & Collaborations:
Patil mentors undergraduate and graduate students in interdisciplinary projects. Notable collaborations include work with Imperial College London and Bristol-Myers Squibb. His lab’s findings have been published in Pharmaceuticals, Journal of Advanced Research, and Computational Biology and Chemistry.
Labs & Teams:
The NanoBio Lab focuses on Alzheimer’s and cancer research, leveraging computational modeling and experimental validation. Current projects explore glycolytic stimulants for ApoE lipidation and AI-driven drug discovery tools.
