Radosveta P Koldamova

Radosveta P Koldamova is a Professor in the Department of Environmental and Occupational Health at the University of Pittsburgh. Her research focuses on translational neuroscience, particularly the genetic and molecular mechanisms underlying Alzheimer's disease.

• Education: MD (1979) and PhD (1994) from Medical Academy Sofia and Bulgarian Academy of Sciences

Her work investigates the role of Alzheimer's-associated genes like APOE, TREM2, and ABCA7 using animal models and advanced techniques including transcriptomic, lipidomic, and epigenetic analysis. She examines how dietary patterns, environmental toxicants, and therapeutic agents modulate disease progression.

Publications highlight her contributions to understanding APOE isoform-specific microglial activation (2021), TREM2 transcriptomic effects (2020), and therapeutic targeting of nuclear receptors (2019). Her research spans Alzheimer's disease models, lipid metabolism, and neuroinflammatory pathways.

• Key Collaborators: Igor Lefterov, Christian M. Wolfe, Nabil M. Nam