Rüdiger Klein

Prof. Dr. Rüdiger Klein is the Director and Head of the Department of Molecules – Signaling – Development at the Max Planck Institute for Biological Intelligence. His research focuses on neuronal circuit formation, cell-cell communication, and neurodegenerative mechanisms using mouse models.

• Research Areas: Cortex development, amygdala circuits, optogenetics, mouse behavior, neurodegeneration studies
• Key Techniques: Genetic circuit manipulation, single-cell RNA sequencing, optogenetics, 2-photon calcium imaging

Scientific Contributions: His work includes ERC-funded studies on synthetic neurocircuit reconstruction, FLRT protein roles in cortical folding, and amyloid-like aggregate toxicity in Huntington's disease.

Advising: Mentored students including Aleksa Petković and Dr. Ylenia Mastrodicasa. Collaborates with Max Planck Institute of Biochemistry departments on proteostasis and neurodegeneration.