معرفی
Ryan Flynn is an Assistant Professor at Boston Children's Hospital in the Stem Cell Program and in the Department of Stem Cell and Regenerative Biology at Harvard University. He leads the Flynn Lab, which focuses on exploring the interface of RNA and glycans through chemical, biochemical, and genetic tools.
- Stem Cell Program, Boston Children's Hospital
- Department of Stem Cell and Regenerative Biology, Harvard University
- Department of Hematology and Oncology
Ryan Flynn completed his BS in Biology at MIT in 2010 and subsequently earned his MD and PhD in Cancer Biology from Stanford University in 2017. After completing his postdoctoral fellowship at Stanford, he established his independent laboratory at Harvard in 2021.
Dr. Flynn's research centers on the groundbreaking discovery of glycoRNA - RNAs modified with complex N-glycans. His work explores how this novel biomolecule class bridges RNA biology and glycosylation, with implications for stem cells, cancer, and regeneration. The Flynn Lab also investigates viral-host RNA interactions, RNA-protein complexes, and RNA structure in living cells using innovative techniques like icSHAPE and PARIS.
Analysis of Dr. Flynn's recent publications (2023-2025) reveals a strong focus on glycoRNA biology, particularly on the cell surface. His work spans multiple disciplines including molecular biology, glycobiology, cancer research, and virology. Key themes include RNA-protein interactions, RNA modification, glycan biosynthesis, and cellular mechanisms involving RNA localization and function.
Dr. Flynn's research has significant implications for understanding fundamental biological processes and developing new therapeutic approaches for cancer and regenerative medicine. His work on cell surface RNA and glycoRNA represents a paradigm shift in our understanding of RNA biology and cellular communication.
