Russell L. Finley, Jr.
استاد · Protein-Protein Interaction Networks
Wayne State Universityمعرفی
Russell L. Finley, Jr. is a Professor at Wayne State University, affiliated with the departments of Molecular Medicine and Genetics and Biochemistry, Microbiology, and Immunology. He is a member of the Karmanos Cancer Institute and serves as Division Director for Education and Graduate Officer for CMMG.
- PhD, SUNY Upstate Medical University (1990)
Dr. Finley's research focuses on understanding regulatory networks that control biological processes and molecular mechanisms of cell division. His lab employs high-throughput technologies such as yeast two-hybrid systems, RNAi screens, and protein microarrays to map gene/protein interaction networks in Drosophila and bacterial pathogens.
His recent publications (2024–2019) highlight work on:
- CHEK2 genetic variants in breast cancer
- Protein interactomes of pathogens (Campylobacter jejuni, Streptococcus pneumoniae, dengue virus)
- Novel cyclin proteins (Cyclin Y, Cyclin J) in cell cycle regulation
- Meta-interactome approaches to improve functional predictions
- Integration of Drosophila interactome and transcriptome data
Dr. Finley contributes to systems biology and bioinformatics through algorithm development (e.g., TraM for graph matching) and interaction confidence scoring methods. His work bridges fundamental cell biology with translational applications in cancer and infectious disease research.
Mentoring: Dr. Finley is accepting new Master's students for 2024/2025 but not new Ph.D. students.
Labs and Teams: His research is conducted within the Karmanos Cancer Institute and the College of Medicine Microbiology and Immunology department at Wayne State University.
