Rupal Gupta

Rupal Gupta is an Associate Professor in the Chemistry department at the CUNY Graduate Center, affiliated with the Chemistry, Biochemistry, and Physics PhD programs. Her research focuses on studying human antimicrobial proteins using advanced biophysical and spectroscopic techniques like EPR and solid-state NMR. The Gupta lab investigates pathogen-host interactions and host defense mechanisms at the chemistry-biology interface. Dr. Gupta holds a PhD from Carnegie Mellon University and an MS from the Indian Institute of Technology, Kanpur.

Her recent work emphasizes structural dynamics of S100 proteins, enzymatic oxygen activation, and metal ion regulation in biological systems. Publications span topics like calcium-mediated protein allostery and substrate promiscuity in dioxygenases. Research tools include computational modeling alongside experimental spectroscopy.

Laboratory activities emphasize atomic-level mechanistic studies of infection-related processes. Contact details include an office in Building 6S Room 214 and a lab homepage at [Gupta Lab URL].