Ranajeet Ghose

Ranajeet Ghose is a Professor in the Department of Chemistry and Biochemistry at City College of New York (CCNY), part of the CUNY system. He leads the Ghose Lab, focusing on structural and mechanistic studies of protein kinases across different biological kingdoms. His research integrates biophysical techniques like NMR spectroscopy, X-ray crystallography, and computational modeling to understand enzyme function in translational control, bacterial signaling, and cancer-related pathways.

Education: PhD from Yale University. Current roles include teaching CHEM 33200 (Physical Chemistry II) and mentoring a diverse team of postdoctoral researchers, PhD students, and undergraduates. The lab collaborates with facilities at the CUNY Advanced Science Research Center (ASRC) and the New York Structural Biology Center (NYSBC), utilizing state-of-the-art NMR, cryo-EM, and X-ray crystallography resources.

Research interests span eukaryotic elongation factor 2 kinase (eEF-2K), bacterial tyrosine kinases (BY-kinases), and mitogen-activated protein kinases (MAPKs). Studies emphasize structure-function relationships, allosteric regulation, and substrate recognition mechanisms. Over 80 peer-reviewed publications highlight contributions to understanding kinase dynamics and their roles in health and disease.

Lab facilities include access to 600-800 MHz NMR spectrometers, solid-state NMR probes, and computational infrastructure. Training opportunities exist for students in protein biochemistry, structural biology, and biophysical techniques. Current openings include postdoctoral positions and PhD programs through CUNY's Graduate Center.