معرفی
Rogerio Amino is a Permanent Researcher and Head of the Biology of Malaria targets and Antimalarials research group at the Institut Pasteur, within the Department of Parasites and Insect Vectors in Paris, France. His research focuses on the early stages of malaria infection, particularly the molecular and cellular mechanisms of Plasmodium sporozoite invasion in the skin and liver, using in vivo imaging and rodent models.
- Institution: Institut Pasteur
- School: Department of Parasites and Insect Vectors
- Department: Biology of Malaria targets and Antimalarials
- Position: Permanent Researcher and Research Group Leader
- Email: rogerio.amino@pasteur.fr
His research interests include host-pathogen interactions, sporozoite motility, immune evasion, cytotoxic antibodies, CD8+ T cell responses, and pre-erythrocytic vaccine development. He employs advanced imaging techniques to study parasite behavior and immune responses in real time. His group investigates three main research axes: (1) molecular determinants of sporozoite infection in skin and liver, (2) host immune protection via antibodies and T cells, and (3) pre-clinical development of multi-antigenic chimeric vaccines. Recent work has revealed novel mechanisms of antibody-mediated sporozoite killing and immune cell recruitment to infected hepatocytes.
The 15 most recent publications reflect a strong focus on malaria immunology and parasite biology, with recurring themes in sporozoite traversal, liver-stage immunity, and vaccine design. Key journals include Nature, Science, Immunity, and Nature Microbiology. The research combines molecular biology, immunology, and advanced imaging to dissect the earliest stages of malaria infection.
Rogerio Amino collaborates extensively with leading institutions worldwide, including:
- Joana Tavares, IBMC, Portugal
- Silvia Boscardin, USP, Brazil
- Robert Seder, NIH, USA
- Fidel Zavala, JHMRI, USA
- Katsuyuki Yui, Nagasaki University, Japan
- Pierre Charneau, Institut Pasteur, France
- Georges Snounou and Roger LeGrand, CEA, France
He mentors multiple PhD students and postdoctoral researchers, including Manuela AGUIRRE BOTERO, Pauline Formaglio, and Xiomara Gaitan. He is actively involved in guiding thesis defenses and research projects. His lab operates within the Institut Pasteur’s collaborative ecosystem, engaging with platforms such as the Center for Vaccinology and Immunotherapy (CVI) and LabEx IBEID.
While no specific scientific awards are listed in the provided text, his high-impact publications and leadership role indicate significant recognition in the field of malaria research.
