معرفی
Robert Saxton is an Assistant Professor in the Departments of Molecular and Cell Biology and Chemistry at the University of California, Berkeley. His research focuses on mechanisms of cell communication governing tissue inflammation, repair, and homeostasis. The Saxton Lab employs structural biology, protein engineering, and mouse models to develop novel immune-targeted therapies. Key projects include studying IL-10 and IL-22 variants for autoimmune disease treatment, understanding immune-epithelial crosstalk in tissue repair, and exploring metabolic-immune interactions in chronic inflammation and cancer.
Robert’s work bridges interdisciplinary approaches, including cryo-EM, receptor pharmacology, and computational modeling. Recent breakthroughs include the structural basis for JAK trans-activation and engineered cytokines with decoupled functions. The lab is affiliated with the Division of Immunology and Molecular Medicine and the Li Ka Shing Center for Biomedical Research.
His research has led to over 30 peer-reviewed articles in top journals like Science, Nature, and Immunity. The Saxton Lab actively collaborates with industry and academic partners to advance translational research in immunology and metabolic disease.
