Robert Lukowski

Prof. Dr. Robert Lukowski is a faculty member at the University of Tübingen, affiliated with the Faculty of Science, Department of Pharmacy and Biochemistry, and leads the research group in Pharmacology, Toxicology and Clinical Pharmacy. He is based at the Institut für Pharmazie, focusing on experimental pharmacology with a strong emphasis on cGMP signaling and ion channel biology.

• University: University of Tübingen
• School: Faculty of Science
• Department: Pharmacy and Biochemistry, Pharmaceutical Sciences, Pharmacology, Toxicology and Clinical Pharmacy
• Email: robert.lukowski@uni-tuebingen.de

His research centers on the role of cGMP and potassium channels (BK, Slack, KCa3.1) in cardiovascular protection, cancer metabolism, and neurological functions. He investigates how these channels regulate cellular signaling in conditions such as ischemia, fibrosis, and neurodegeneration. His work bridges molecular pharmacology with translational applications in cardiology, oncology, and neuroscience.

The recent publications show a strong trend in understanding ion channel function in disease models, particularly in myocardial protection, metabolic reprogramming in cancer, and pain/itch pathways. The use of genetically encoded biosensors and mouse models is a hallmark of his research approach. Topics span from mitochondrial function to synaptic plasticity and immune cell signaling.

Scientific Commentary and Recognition:

• Regular contributor to Faculty Opinions (F1000), recommending high-impact studies in cardiovascular and molecular pharmacology.

Advising and Research Leadership: Leads a multidisciplinary team including postdoctoral researchers, PhD candidates, and laboratory staff, indicating active mentorship and grant-funded research. His collaborations span multiple institutions and involve advanced imaging, molecular biology, and physiological assays.

Laboratory and Research Environment: The "Experimentelle Pharmakologie" lab at Auf der Morgenstelle 8 is equipped for cutting-edge research in signal transduction, utilizing biosensors, transgenic models, and functional assays to study cGMP and ion channel dynamics in health and disease.