معرفی
Professor Robert Feil leads the Department of Signal Transduction & Transgenic Models at the Interfaculty Institute for Biochemistry, University of Tübingen. His research focuses on cGMP signaling pathways across cardiovascular, neurological, and cancer contexts, utilizing "in vivo biochemistry" and advanced optical imaging technologies in transgenic mouse models.
- Current affiliations: Spokesperson for DFG Research Training Group GRK 2381 (2019-present) and member of GRK 2816
- Research highlights: Mechanosensitive cGMP signaling, tumor-vascular interactions, CNP/GC-B signaling in kidney development, and novel insights into atherosclerosis mechanisms
Recent work emphasizes cell fate mapping through CreER technology and real-time cGMP visualization in living systems. His lab has produced significant findings on vascular smooth muscle cell plasticity and macrophage-like cell transdifferentiation in atherosclerotic plaques.
Key trainees include:
- PhD candidates: Kevin Dervishi (mechanosensitive signaling), Alisa Groh (tumor vessel signaling), Shahzad Munir (hippocampal signaling), Daniel Pinto Quintero (platelet signaling), and Asli Pektas (developmental physiology)
- Past doctoral researchers: Timo Kopp (2024 graduate), Daniel Stehle (2023 graduate)
Technological innovations:
- Developed CreERT2 for inducible gene targeting
- Created cGMP biosensors for in vivo imaging
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