Richard T O'Neil

Richard T. O'Neil, PhD is an Assistant Professor at the Medical University of South Carolina's College of Medicine in the Department of Pharmacology & Immunology. His research focuses on immune cell engineering for oncologic applications, utilizing transposon-based genome modification to develop advanced cellular therapeutics.

• Key methodologies: Single-cell transcriptomics, Flow cytometry, In vivo imaging
• Therapeutic targets: Solid tumor microenvironment, Immune checkpoint regulation

Recent work demonstrates his leadership in transposon-engineered T cell platforms (2024) and metabolic regulation of immune cells (2023). His publications span Cancer Biology, Immunology, and Neurogenetics, with high-impact contributions in Nature and Nature Communications.