Richard Neubig

Richard Neubig is a Professor in the BioMolecular Science Gateway at Michigan State University, focusing on G protein-coupled receptors and Regulators of G Protein Signaling (RGS proteins). His lab investigates RGS proteins' roles in CNS disorders, developing the only CNS-penetrating RGS4 inhibitor with antidepressant-like effects and pain reduction properties in animal models.

• Key Research: GNAO1 gene mutations in human genetic epilepsies/movement disorders
• Drug Development: MRTF/SRF pathway inhibitors for fibrosis and melanoma resistance
• Expertise: Protein dynamics, small molecule screening, and signal transduction mechanisms

Article Trends: Recent work spans bacterial pathogenesis (Brucella ovis RND transporters), melanoma drug resistance (Rho/MRTF-SRF inhibition), fibrosis treatment (ATP12A, MRTF/SRF), and orphan receptor classification (GtoPdb). His studies often bridge pharmacology, neuroscience, and molecular biology, with a focus on translational applications for neurological and fibrotic diseases.