معرفی
Richard Maas is a Professor at Harvard Medical School affiliated with Brigham and Women's Hospital, leading the Maas Laboratory focused on vertebrate organ development and regeneration. His research spans two primary areas: (1) Systems-based Consortium for Organ Design and Engineering (SysCODE), a $24M NIH-funded initiative for stem cell-based organ regeneration, and (2) mechanistic studies of Pax6, Hox, and related genes in eye, craniofacial, pancreatic, and kidney development.
- Key affiliations: Brigham and Women's Hospital, Harvard Medical School, NIH SysCODE Consortium
- Research domains: Developmental genetics, gene networks, interdisciplinary regenerative medicine
His lab employs experimental embryology, molecular genetics, and computational approaches to unravel evolutionary conserved pathways in organogenesis, with applications to human birth defects. Current projects include regenerating tooth germ, pancreatic islets, and heart valves through multidisciplinary collaboration.
Scientific contributions include:
- Establishing causal roles of genes like ROBO2, NFIA, and SUMO1 in renal and craniofacial defects
- Developing iSyTE computational platform for eye gene discovery
- Characterizing molecular blueprints for tissue engineering through genomic/proteomic integration
The lab actively trains students and postdocs through NIH-funded interdisciplinary programs, with a focus on bridging developmental biology and bioengineering.
