Richard Higashi

Richard Higashi is a Professor in the Department of Toxicology and Cancer Biology at the University of Kentucky. He serves as Associate Director of the Redox Metabolism Shared Resource Facility at the Markey Cancer Center and is a member of the Cancer Research Priority Initiative and Molecular and Cellular Oncology Research Program.

• Education: PhD (1987) and BS (1977) from University of California-Davis and University of Hawaii respectively
• Research: Pioneering stable isotope-resolved metabolomics to study cancer metabolism, metabolic reprogramming, and tumor microenvironment dynamics.
• Grants: 82 active/finalized grants including NCI-funded projects on mitochondrial redox capacity and immunosuppressive tumor microenvironment targeting.
• Collaborations: Key partnerships with Anthony N. Lane on cancer metabolism and Qi Wang on colorectal cancer immunotherapy.

Scientific Impact: Over 13,000 citations, 47 h-index, with 136 research outputs including 110 original articles. Current projects focus on mitochondrial targeting, metabolic checkpoint inhibition, and precision oncology platforms.