معرفی
Ricardo Aguas serves as Associate Professor at the University of Oxford's Nuffield Department of Medicine, with primary affiliation at the Mahidol Oxford Tropical Medicine Research Unit (MORU) in Bangkok. He leads the MAEMOD research group focused on mathematical modeling of malaria transmission dynamics and intervention strategies across Southeast Asia.
His research spans two critical domains: malaria elimination and viral host adaptation. For malaria, he develops dynamic transmission models for targeted elimination strategies (METF), specializing in mass drug administration (MDA) optimization through individual-based simulations across diverse epidemiological settings. His viral research pioneers machine learning approaches for genotype-to-phenotype mapping, demonstrating how multi-class algorithms can identify conserved genetic signatures determining host specificity in RNA viruses, particularly relevant for pandemic preparedness.
Publication analysis reveals a methodological evolution from foundational malaria transmission modeling (2008-2015) to integrated approaches combining epidemiological, economic, and conflict dimensions (2020-2023). Recent work addresses vaccine policy under uncertainty (Thailand), pandemic responses in conflict zones (Syria), and cost-effectiveness of malaria interventions (Myanmar), reflecting increasing real-world policy relevance.
His laboratory work prominently features principal component analysis of viral genomes and superimposed antigenic mapping, with key visualizations showing SARS-CoV-2 spike protein sequences and MDA simulation outputs across 800-village networks.
