معرفی
Ravi Radhakrishnan is a Professor and Herman P. Schwan Department Chair of Bioengineering at the University of Pennsylvania, with primary affiliations in the Department of Bioengineering and Department of Chemical and Biomolecular Engineering. His research focuses on creating Digital Twin Models for cancer treatment and next-generation therapeutics using nanomedicine.
- Research spans molecular and cellular scales
- Integrates statistical mechanics, machine learning, and high-performance computing
- Collaborates with pharmacologists, oncologists, and biophysical chemists
Research Highlights
The Radhakrishnan Lab investigates:
- Intracellular Trafficking via nano-to-micron-scale computational modeling of biological membranes
- Mutation-driven Oncogenic Activation using molecular dynamics and protein language models
- AI-enabled Multiscale Modeling for insilico oncology and personalized medicine
- Targeted Drug Delivery dynamics with nanocarriers optimized through pharmacokinetic models
Funding & Collaborations
Supported by grants from the US National Science Foundation, NIH, DOE, and European Research Council, with industry partnerships including Sanofi, Amgen, and Siemens Healthineers. Research utilizes physics-informed neural networks and hybrid multiscale methods validated against in vivo and in vitro experiments.
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