Rafael Giraldo

Rafael Giraldo is a National Centre for Biotechnology (CNB-CSIC) Research Professor in the Department of Microbial Biotechnology since 2019. His career spans over three decades at the Centro de Investigaciones Biológicas (CIB-CSIC), where he held progressively senior roles from 1995-2018.

• Current affiliation: CNB-CSIC (2019-)
• Previous roles: CIB-CSIC (1995-2018)
• Academic memberships: SEBBM, SBE, SEM (Vice-President 2015-), ASM, ISPB

His research focuses on:

• Structural & functional biology of DNA replication proteins
• Amyloid proteinopathies in bacterial models
• Synthetic biology applications for protein assembly
• Optogenetics control of protein aggregation

Recent publications demonstrate his pioneering work in:

• Engineering bacterial amyloids (2021-2024)
• Elucidating DNA replication mechanisms (2023)
• Developing synthetic prionoid systems (2016-2020)

Scientific recognition includes:

• Fellow, Academia Europaea (2010)
• Corresponding Fellow, Spanish Royal Academy of Pharmacy (2023)
• Member, CSIC Research Ethics Committee (2018-2020)

His Laboratory of Synthetic Bacterial Amyloids explores protein conformational dynamics using:

• Cell-free expression systems
• Cytomimetic lipid vesicles
• Structural methods (NMR, EM, AFM)