ROMAN PEREZ FERNANDEZ

Roman Perez Fernandez is a Professor at the Department of Physiology, University of Santiago de Compostela. He is affiliated with the Faculty of Medicine and Dentistry, and leads research at the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) and the Strategic Grouping in Materials (AEMAT). His work focuses on designing bioactive compounds and materials, particularly vitamin D analogues and stem cell therapies. He holds a PhD from the University of Santiago de Compostela (1987) with a thesis on adrenal androgen physiology.

Research interests include molecular mechanisms of cancer progression, anti-fibrotic therapies, and stem cell secretome applications. Notable areas include breast cancer metastasis regulation via POU1F1 transcription factor, and development of novel vitamin D-based drugs targeting oncologic and metabolic conditions. His studies also explore the therapeutic potential of human uterine cervical stem cells in regenerative medicine and anti-inflammatory treatments.

Publications highlight advancements in: 1) Design of anti-cancer vitamin D analogs with reduced calcemic side effects; 2) Role of p63 in hepatic glucose metabolism and fibrosis; 3) Mechanisms of cancer stem cell reprogramming; 4) Anti-inflammatory effects of conditioned stem cell media in ocular and gastrointestinal disorders. His work bridges organic chemistry, molecular biology, and clinical applications.

Awards and grants are not explicitly listed, but his extensive publication record (over 70 papers from 1987–2025) reflects sustained research excellence. He collaborates across disciplines including material science (AEMAT) and molecular medicine (CIMUS). Current projects involve optimizing drug delivery systems using hydrogels and cyclodextrin complexes for targeted therapies.