معرفی
Dr. Qing Fan is a Research Associate Professor at the Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine. His research focuses on identifying and characterizing cell surface carbohydrates and glycoproteins essential for herpes simplex virus (HSV) entry and cell fusion, particularly the glycoproteins gB and gL. He investigates interactions between gB and its receptor PILRa, as well as the functional roles of glycoproteins gD, gH, and gL in viral entry mechanisms. Dr. Fan holds a PhD from the Chinese Academy of Sciences (1998).
- Education: PhD in Microbiology (Chinese Academy of Sciences, 1998)
His research interests span HSV entry dynamics, glycoprotein structure-function relationships, and host-virus interaction mechanisms. Recent work includes leveraging proximity labeling to identify cellular factors in alphaherpesvirus infection and discovering TMEFF1 as a brain-specific HSV restriction factor. His studies often integrate mutagenesis, structural biology, and cell culture models (e.g., Drosophila S2 cells) to dissect viral entry pathways.
Publications highlight a focus on glycoprotein interactions (e.g., gH/gL-gB interfaces) and functional domains critical for fusion. His work bridges virology, molecular biology, and structural studies to advance understanding of HSV pathogenesis.
