معرفی
Premila P. Samuel Russell is an Assistant Professor of Chemistry at Saint Louis University (SLU), within the School of Science and Engineering. Her research focuses on computational modeling of human cell environments to study biomolecular dynamics and hidden states inaccessible via traditional experiments. She integrates in silico simulations with experimental assays for validation.
Education:
- B.A. in Chemistry, Berea College, Kentucky, 2012
- Ph.D. in Biochemistry, Rice University, Texas, 2017
Research Interests:
- Computational Chemistry: Developing atomistic models of cytoplasmic environments to simulate protein behavior.
- Biophysics: Exploring protein folding, misfolding, and interactions in cellular contexts.
- Protein Dynamics: Investigating enzyme choreography and metabolon formation through all-atom simulations.
- Drug Design: Analyzing hemoglobin structure for therapeutic applications like Voxelotor.
Her recent work emphasizes 'cells-on-computers' simulations and high-throughput experimental assays, addressing limitations in spatial-temporal resolution of conventional methods.
Awards:
- Cooley’s Anemia Foundation Research Fellowship (2023)
- D.E. Shaw Research Women’s Fellowship (2021)
- Rice University’s George J. Schroepfer Awards for Thesis and Research Excellence (2017–2018)
Her lab (Premila Research Group) bridges computational and experimental approaches to advance understanding of biomolecular systems. Contact: premila.russell@slu.edu at Monsanto Hall, SLU.
