Pratik Shah

Dr. Pratik Shah is an Assistant Professor in the Department of Pathology at the University of California, Irvine (UCI) School of Medicine. He leads a cutting-edge research group focused on translational artificial intelligence and biomedical technologies to advance diagnostic imaging, uncover biological mechanisms, and enable clinical deployment of digital therapeutics.

• Institution: University of California, Irvine
• School: School of Medicine
• Department: Department of Pathology
• Academic Rank: Assistant Professor
• Email: pratik.shah@uci.edu

Dr. Shah's research lies at the intersection of computational medicine, artificial intelligence, and biomedical imaging. His work emphasizes developing interpretable and explainable AI systems that enhance model effectiveness, safety, and clinical utility. Key research areas include generative AI for nondestructive histopathology, deep learning for medical image analysis, AI-driven clinical decision support for infectious diseases, and multimodal imaging for biological insights. His lab is dedicated to creating equitable and responsible technologies to improve diagnosis and treatment of cancer, infectious diseases, and neurological disorders.

The recent publications highlight a strong trend in applying deep learning to digital pathology, particularly in computational staining and tumor detection from non-stained images. There is a consistent focus on developing interpretable AI tools for medical image segmentation, with applications in cancer diagnostics, sepsis detection, and dental imaging. The research spans from foundational AI methods to clinical validation, showing a trajectory toward regulatory science and real-world deployment of AI in healthcare.

• MIT NEWS feature on computational staining research
• SPIE publication selected for Deep-Dive spotlight session
• SPIE publication selected for oral presentation
• IEEE BioInformatics and BioEngineering publication selected for oral presentation

Dr. Shah has mentored a diverse group of students and postdoctoral associates, including PhD candidates in Mechanical Engineering at MIT and undergraduate researchers in Electrical Engineering and Computer Science. His trainees have contributed to high-impact publications in journals like JAMA Network and conferences like IEEE EMBC. He has fostered collaborations with institutions including Stanford, UCSF, and the FDA, indicating strong research outreach and interdisciplinary partnerships. His lab has received recognition through media features and conference selections, reflecting the significance and innovation of his work in AI for healthcare.

Dr. Shah leads a multidisciplinary research team comprising postdoctoral associates, graduate students, research staff, and student researchers, primarily focused on machine learning and medicine. The lab has strong ties to MIT, where much of the prior research was conducted, and maintains collaborations with clinical and engineering experts across the US.