Philippe Collas

Philippe Collas is a Professor and Head of Department at the Department of Basic Medical Sciences, University of Oslo. His research focuses on epigenetics, chromatin structure, and 3D genome organization, particularly during adipogenesis, senescence, and cancer progression.

• Email: philippe.collas@medisin.uio.no
• Research Keywords: Stem cells, Epigenetics, Chromatin Structure, Biochemistry, Genomics, Medical Sciences

His work explores the role of nuclear lamins, laminopathies, and non-coding RNAs (e.g., HOTAIR) in regulating gene expression, chromatin dynamics, and metabolic resilience. Recent studies highlight mechanisms in adipose stem cell differentiation, PML nuclear bodies, and histone modifications influencing heterochromatin formation. He collaborates extensively on topics like triple-negative breast cancer, telomere integrity, and CD8+ T cell maintenance, integrating genomic and computational models to map nuclear architecture.

Key trends in his publications include the interplay between chromatin-lamina interactions, epigenetic reprogramming, and metabolic stress responses. His lab employs advanced genomic techniques (e.g., Chrom3D, Hi-C) and single-cell analysis to decode 3D genome architecture in stem cells and cancer models.