Peter Tessier

Peter Tessier is the Albert M. Mattocks Professor of Pharmaceutical Sciences at the University of Michigan, with an affiliation in Biomedical Engineering (BME). His research focuses on developing cutting-edge technologies for designing, discovering, and delivering therapeutic antibodies and biologics, with applications in drug delivery, neurodegenerative diseases, and cancer therapy. The Tessier Lab integrates experimental and computational approaches to advance protein engineering and high-throughput screening tools.

Research interests include bio-nanotechnology, molecular imaging, and the development of bispecific antibodies for brain delivery. The lab also explores machine learning and AI to optimize antibody properties and predict therapeutic efficacy. Notable projects involve antibody engineering for targeting Alzheimer’s, Parkinson’s, and cancer, alongside non-invasive gene modulation in the brain.

Key areas of innovation include conformational antibodies for disease detection, agonist antibodies for immune activation, and novel drug delivery systems. The lab’s interdisciplinary approach bridges bioengineering, computational biology, and clinical applications.

Scientific contributions span over 100 publications, emphasizing antibody design, protein aggregation, and translational medicine. Collaborations focus on advancing therapeutic antibodies from discovery to clinical application.