معرفی
Paul Dupree is a Professor in the Department of Biochemistry at the University of Cambridge, leading the Dupree Group. His research focuses on understanding the biosynthesis and function of plant cell wall polysaccharides, particularly xylans, glucomannans, and cellulose. His work integrates functional genomics, biochemical assays, and structural analysis to elucidate polysaccharide synthesis mechanisms and their roles in plant growth and environmental interactions.
Research Interests: Central to his work are questions about how plant cell walls are constructed, how polysaccharide structures influence mechanical properties and microbial interactions, and their nutritional/agricultural applications. Techniques employed include proteomic screening, mutant analysis in Arabidopsis, and advanced imaging like solid-state NMR to probe molecular architecture.
Recent Work Trends: Recent publications emphasize structural analysis of cell wall components (e.g., softwood macrofibrils, eudicot glucomannan), enzymatic degradation mechanisms, and evolutionary aspects of polysaccharide biosynthesis across plant lineages. Studies also explore biotechnological applications like biomass pretreatment for biofuel production.
Awards & Recognition: No specific awards mentioned in the provided texts.
Advising & Labs: Supervises graduate students (e.g., Thomas Foets, Helena Rannikmae) and supports postdoctoral researchers. The Dupree Group actively recruits interns and offers opportunities in plant cell wall research. Their lab focuses on biochemical assays, mutant analysis, and structural biology tools.
