
معرفی
Dr. Paul Christopher Michael Fogg is a Senior Lecturer at the University of York, specializing in the Department of Biology. His research focuses on the mechanisms and implications of horizontal gene transfer (HGT) in bacterial evolution and antibiotic resistance dissemination.
Research Interests: HGT drives bacterial adaptation through conjugation, transformation, and transduction. Dr. Fogg's lab investigates gene transfer agents (GTAs), virus-like entities that indiscriminately transfer DNA between bacteria, with particular emphasis on their role in spreading antibiotic resistance genes and virulence factors. His work explores GTA regulation, assembly mechanisms, and ecological impact.
Scientific Contributions: Recent publications examine GTA terminase function in Rhodobacter capsulatus and future directions in prokaryotic chromosome research. His studies address critical gaps in understanding how GTAs maintain evolutionary advantages despite selfless behavior.
- Scientific Awards:
- Sir Henry Dale Fellow
- Sir Henry Dale Senior Research Fellow
Laboratory Focus: The lab integrates biochemical, structural, and molecular approaches to dissect GTA-phage differences, with implications for biotechnology and combating antibiotic resistance. Current projects include structural basis of HGT, domesticated virus applications, and spatio-temporal host recognition analysis.
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