Patrick Duriez

Dr. Patrick Duriez is a Protein Biochemist affiliated with the Cancer Sciences School at the University of Southampton. He established the Protein Facility in 2006, leveraging over 30 years of molecular biology experience and 20 years specializing in protein expression/purification. The facility has produced over 100 recombinant proteins, contributing to 45+ publications. His research focuses on cancer immunotherapy and recombinant protein production, integrating steps from cloning to quality control. Collaborations with structural biologists in the Institute of Life Sciences highlight interdisciplinary work.

Recent research emphasizes MHC class I immunopeptidome editing, SARS-CoV-2 nucleocapsid diagnostics, and oncogenic protein stabilization. Publications span immunology, biochemistry, and structural biology, reflecting his expertise in protein engineering and cancer-related biomolecules. The Protein Facility’s outputs support both academic research and clinical applications, particularly in immunotherapy development.

Dr. Duriez’s work bridges basic science and translational medicine, with notable contributions to understanding protein interactions in cancer pathways and developing diagnostic tools for global health challenges.