Partha Sarkar

Dr. Partha Sarkar is an Associate Professor at the University of Texas Medical Branch, affiliated with the Department of Neurology, Neuroscience, Cell Biology and Anatomy and the Mitchell Center for Neurodegenerative Disorders. He holds a PhD in Molecular Biophysics from the Indian Institute of Science and specializes in mechanisms of neurodegenerative disorders.

His research focuses on DNA damage repair pathways in Huntington's disease, myotonic dystrophy, and spinocerebellar ataxia. Key investigations include polyglutamine expansion pathologies, mitochondrial DNA maintenance, and early synaptic vulnerability in Alzheimer's disease. His work bridges molecular biophysics with clinical neurology to develop novel therapeutic strategies.

Dr. Sarkar's 15 most recent publications demonstrate a consistent focus on DNA repair mechanisms in neurodegeneration, with emerging work in cancer radiotherapy combinations. His articles frequently utilize advanced molecular techniques and cross-disciplinary approaches.

Awards:

• Josephine T. Morse Endowed Professorship in Neuropathology (2006)
• Weil Award for neuropathology research (2001)
• Departmental Teaching Award (2006)

He leads multiple NIH-funded projects investigating HTT-mediated DNA repair and currently supervises doctoral candidates in neurodegeneration research. His laboratory utilizes cutting-edge genomic and proteomic approaches to study chromatin remodeling in disease models.