Paolo Guglielmi

Paolo Guglielmi is an Associate Professor at the Department of Chemistry and Pharmaceutical Technology, Sapienza University of Rome. His research and teaching focus on medicinal chemistry, particularly enzyme inhibitors for cancer and neurodegenerative diseases. He graduated with honors in Chemistry and Pharmaceutical Technologies in 2014 and earned a PhD in Pharmaceutical Sciences in 2018.

• University: Sapienza University of Rome
• Department: Department of Chemistry and Pharmaceutical Technology
• Academic Rank: Associate Professor

His research centers on:

• Monoamine Oxidase B (hMAO-B) Inhibitors for neurodegenerative diseases
• Carbonic Anhydrase IX/XII (hCA IX/XII) Inhibitors for tumor therapy
• Metal-Organic Frameworks (MOFs) for anticancer drug delivery
• Microwave-Assisted Synthesis of bioactive compounds

Publication trends highlight:

• 2025: Coumalic acid-based CA inhibitors with molecular modeling
• 2024: Chiral metabolite HPLC resolution studies
• 2023: Hybrid CAI-CORM molecules for rheumatoid arthritis
• 2022: MAO inhibitor patent reviews and MOF biomedical applications
• 2021: Dual-action H. pylori/AGS inhibitors and halogenated MAO-B modulators

Scientific recognition:

• FEBS Letters Poster Award (2019)
• Member of Italian Chemical Society

He has received national/university funding including a PRIN project as Principal Investigator and leads Laboratory 212 for analytical and synthetic research.